{"id":7819,"date":"2023-03-04T16:04:35","date_gmt":"2023-03-04T16:04:35","guid":{"rendered":"https:\/\/informatiacluj.ro\/proteina-banala-care-poate-combate-covid-si-alte-virusuri-gripale-ar-putea-salva-vietile-oamenilor\/"},"modified":"2023-03-04T16:04:35","modified_gmt":"2023-03-04T16:04:35","slug":"proteina-banala-care-poate-combate-covid-si-alte-virusuri-gripale-ar-putea-salva-vietile-oamenilor","status":"publish","type":"post","link":"https:\/\/informatiacluj.ro\/proteina-banala-care-poate-combate-covid-si-alte-virusuri-gripale-ar-putea-salva-vietile-oamenilor\/","title":{"rendered":"Proteina banal\u0103 care poate combate COVID \u0219i alte virusuri gripale. Ar putea salva vie\u021bile oamenilor"},"content":{"rendered":"<div>\n<p><em><strong>Cercet\u0103torii de la Universitatea din Michigan au descoperit c\u0103 proteina H84T-BanLec este eficient\u0103 \u00eempotriva tuturor coronavirusurilor cunoscute care infecteaz\u0103 oamenii.<\/strong><\/em><\/p>\n<p><em>La 13 ianuarie 2020, era publicat\u0103 o lucrare care sus\u021binea c\u0103\u00a0 au descoperit proteina H84T-BanLec\u00a0 care poate s\u0103 combate COVID \u0219i poate fi folosit\u0103 pentru a lupta \u0219i \u00eempotriva tuturor virusurilor gripale.<\/em><\/p>\n<p>O s\u0103pt\u0103m\u00e2n\u0103 mai t\u00e2rziu, primul caz confirmat de SARS-CoV-2 a declan\u0219at pandemia de COVID-19 \u00een toat\u0103 lumea.<\/p>\n<p>Interesant este c\u0103, \u00eenainte de apari\u021bia virusului care le-a oprit temporar activitatea, echipa din SUA a analizat aceste terapii derivate din banane pentru coronavirus, scrie The Brighter Side.<\/p>\n<p>Cercet\u0103torii de la Universitatea din Michigan, SUA, au descoperit c\u0103 proteina H84T-BanLec este eficient\u0103 \u00eempotriva tuturor coronavirusurilor cunoscute, care infecteaz\u0103 oamenii inclusiv sindromul respirator din Orientul Mijlociu (MERS), SARS original \u0219i SARS-CoV-2, inclusiv varianta Omicron.<\/p>\n<p><strong>Lucrarea lor a fost publicat\u0103 \u00een Cell Reports Medicine.<\/strong><\/p>\n<p><strong>H84T-BanLec este o protein\u0103 cu abilit\u0103\u021bi remarcabile de blocare viral\u0103<\/strong><\/p>\n<p>H84T-BanLec este derivat dintr-o lectin\u0103 (o protein\u0103 care leag\u0103 carbohidra\u021bii) izolat\u0103 din fructul bananei. Aceasta are abilit\u0103\u021bi remarcabile de blocare viral\u0103 prin legarea de glicani cu un con\u021binut ridicat de manoz\u0103, o monozaharid\u0103 de tip zah\u0103r prezent\u0103 la suprafa\u021ba virusurilor, dar foarte rar pe celulele umane s\u0103n\u0103toase.<\/p>\n<p>Dup\u0103 legare, virusul nu poate p\u0103trunde \u00een celule pentru a le infecta. Folosind microscopia cu for\u021b\u0103 atomic\u0103 \u0219i metode conexe, echipa a confirmat c\u0103 H84T dezvolt\u0103 leg\u0103turi multiple puternice cu proteina spike, ceea ce, spun cercet\u0103torii, explic\u0103 de ce este dificil pentru un coronavirus s\u0103 fie rezistent la lectin\u0103.<\/p>\n<p><strong>Utilizarea H84T-BanLec \u0219i \u00eempotriva cancerului?<\/strong><\/p>\n<p>\u00cen ciuda poten\u021bialului lor antiviral, lectinele au fost evitate ca posibile terapii, deoarece sunt proteine \u200b\u200bcare pot stimula sistemul imunitar \u00eentr-un mod posibil d\u0103un\u0103tor, explic\u0103 cercet\u0103torii.<\/p>\n<p>Cu toate acestea, H84T-BanLec a fost modificat pentru a elimina acest efect \u0219i nu a prezentat efecte d\u0103un\u0103toare la animale. Echipa are \u00een vedere acum un spray nazal, care ar putea fi utilizat pentru a preveni sau trata infec\u021biile cu coronavirus \u0219i grip\u0103.<\/p>\n<p>Ei vor s\u0103 analizeze utilizarea H84T-BanLec \u00eempotriva cancerului, deoarece celulele canceroase, ca \u0219i virusurile, au glicani de manoz\u0103 mari pe suprafa\u021ba lor.<\/p>\n<p><strong>Terapia a func\u021bionat!<\/strong><\/p>\n<p>\u201eLa vremea respectiv\u0103, credeam c\u0103 MERS va fi \u021binta cea mai important\u0103, din cauza ratei sale de mortalitate de 35%\u201d, a afirmat David Markovitz, profesor de medicin\u0103 intern\u0103 la Divizia de Boli Infec\u021bioase de la Universitatea din Michigan. MERS, sau sindromul respirator din Orientul Mijlociu, a provocat un focar scurt \u00een 2015 \u0219i a dus la 858 de decese.<\/p>\n<p>\u201eC\u00e2nd a ap\u0103rut COVID-19, am vrut s\u0103 studiem poten\u021bialul terapiei \u0219i am descoperit c\u0103 este eficient\u0103 \u00eempotriva oric\u0103rui tip de coronavirus, in vitro \u0219i in vivo\u201d, a spus Markovitz. \u201eAdministrat\u0103 sistemic sau prin nas la animale sau administrat\u0103 profilactic sau terapeutic la \u00eenceputul bolii, aceasta a func\u021bionat\u201d, a continuat el.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Cercet\u0103torii de la Universitatea din Michigan au descoperit c\u0103 proteina H84T-BanLec este eficient\u0103 \u00eempotriva tuturor coronavirusurilor cunoscute care infecteaz\u0103 oamenii. La 13 ianuarie 2020, era publicat\u0103 o lucrare care sus\u021binea c\u0103\u00a0 au descoperit proteina H84T-BanLec\u00a0 care poate s\u0103 combate COVID \u0219i poate fi folosit\u0103 pentru a lupta \u0219i \u00eempotriva tuturor virusurilor gripale. O s\u0103pt\u0103m\u00e2n\u0103 mai [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":7820,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"tdm_status":"","tdm_grid_status":"","footnotes":""},"categories":[34],"tags":[35],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Proteina banal\u0103 care poate combate COVID \u0219i alte virusuri gripale. Ar putea salva vie\u021bile oamenilor - InformatiaCluj.ro<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/informatiacluj.ro\/proteina-banala-care-poate-combate-covid-si-alte-virusuri-gripale-ar-putea-salva-vietile-oamenilor\/\" \/>\n<meta property=\"og:locale\" content=\"ro_RO\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Proteina banal\u0103 care poate combate COVID \u0219i alte virusuri gripale. Ar putea salva vie\u021bile oamenilor - InformatiaCluj.ro\" \/>\n<meta property=\"og:description\" content=\"Cercet\u0103torii de la Universitatea din Michigan au descoperit c\u0103 proteina H84T-BanLec este eficient\u0103 \u00eempotriva tuturor coronavirusurilor cunoscute care infecteaz\u0103 oamenii. 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